ClotCare: Blood Clots, Stroke, Heart Attack
Wednesday, May 22, 2024
Home   |   DVT/PE   |   Blood Clots   |   Coumadin/Warfarin   |   New Patients   |   Self Testing   |   Email List   |   Donate

Pick a Topic:

Find info on a:

We subscribe to the HONcode principles of the HON Foundation. Click to verify.
ClotCare complies with the HONcode standard for trustworthy health
verify here.

ClotCare is a member of the Coalition to Prevent Deep Vein Thrombosis (DVT Coalition)  ClotCare is a member organization of the Coalition to Prevent Deep Vein Thrombosis. Click here to learn more about the Coalition to Prevent Deep Vein Thrombosis and DVT Awareness Month, which is held each March.

Anticoagulation Education and Reduced Bleeding in the Elderly

Henry I. Bussey, Pharm.D.
October 2004

Review: Kagansky N, Knobler H, Rimon E, Ozer Z, Levy S. Safety of Anticoagulation Therapy in Well-informed Older Patients. Arch Intern Med. 2004 Oct 11;164(18):2044-50.

A recent study from Israel evaluated factors that correlated with major bleeding episodes in patients 80 years of age and older on anticoagulation therapy. 323 patients who were followed for a mean of 29 months had relatively few major bleeding events (22 events, 2.88 events per 100 patient-years). Three factors (low level of education about anticoagulation, INRs > 3, and those taking more than 7 medications) each was associated with an increased risk of major bleeding. However, insufficient patient education demonstrated the strongest relationship by far. Those who rated their educational experience as insufficient had an 8.8 fold greater risk (odds ratio) of having a major bleed. For INRs > 3 and more than 7 medications, the odds ratios were 1.08 and 6.1, respectively.

This report appears to be the first that has demonstrated such a strong relationship between patient education (or lack thereof) and major bleeding risk.

Ask a question about blood clots or anticoagulant medications Have questions? Ask ClotCare. Send questions by email to

ClotCare is a 501(c)(3) non-profit organization generously supported by your tax-deductible donations and grants from our industry supporters.

Blood Clot Activities Calendar

New Postings:

Click here to view full list of new postings
ClotCare Home | New Postings | Patient Postings | Clinician Postings | Join Our Email List | Useful Web Links
CE Opportunities | Training Programs | DVT & PE Stories | Editorial Board | Financial Support
About ClotCare | DVT Coalition | Donate to ClotCare | Contact Us
Key topics discussed on ClotCare include: Blood Clots | Deep Vein Thrombosis (DVT) | Pulmonary Embolism (PE) | Atrial Fibrillation (A. Fib or AF) | Heart Attack | Stroke | Transient Ischemic Attack (TIA) | Mini Stroke | Bleeding Complications | Vascular Surgery | Surgical Blood Clot Removal | Warfarin | Coumadin | Lovenox | Low Molecular Weight Heparin (LMWH) | Heparin | Anticoagulants | Plavix | Aspirin | Antiplatelets | Blood Thinners
Copyright 2000-2018 by ClotCare. All rights reserved.
Terms, Conditions, & Privacy | Image Copyright Information
19260 Stone Oak Parkway, Suite 101 | San Antonio, TX 78258 | 210-860-0487
Send comments to
Wednesday, May 22, 2024